• Supports Brain Health*
• Supports Cognitive Health*
• Supports Healthy Gut-Brian Axis
• Supports Brain Health*
• Supports Cognitive Health*
• Supports Healthy Gut-Brian Axis
Leaky Gut: A Growing Focus in Gut Barrier and Health Research
The concept of “leaky gut,” where the intestinal barrier becomes more permeable, is a growing area of research and interest, with potential links to various health conditions.
The Gut-Brain Axis is currently a hot topic, and it’s only getting bigger.
The Global Interest in “Exosome” is Continuously Rising.²
By 2035, the probiotics market for antibiotic recovery is set to hit $116.2 billion, growing at 8.6% CAGR.²
Gut Integrity Matters
ExoBDNF™ Protects Against Leaky Gut
A weakened gut barrier allows harmful substances to enter the body, triggering inflammation
and immune disruptions that may impair brain function. Protecting the gut is essential for
maintaining brain health. ExoBDNFTM reinforces intestinal barrier proteins such as tight junction protein, reducing permeability and strengthening gut integrity. It also supports a healthier
microbiome by promoting beneficial bacteria and selectively targeting harmful bacteria like
C. difficile.
ExoBDNF™ Maintains Healthy Intestinal Function
Administration of ExoBDNF derived exosome-like vesicles (ExoBDNF-EVs) in aged mice resulted in a 109% increase in tight junction protein (ZO-1) expression and a 43% reduction in intestinal permeability, demonstrating that ExoBDNF-EVs help maintain healthy intestinal function.
ExoBDNF™ Maintains Healthy Gut Flora
In the aging animal model, the gut microbiota of the aging group (Aging/C) was dominated by specific bacterial species compared to the control group (C). Treatment with ExoBDNF-EVs (Aging/ExoBDNF-EVs) modulated the microbial composition toward a more balanced and diverse profile relative to the aging group.
ExoBDNF-Extra Benefits
By 2035, the probiotics market for antibiotic recovery is set to hit $116.2 billion, growing at 8.6% CAGR.
ExoBDNF™-Targeting Pathogenic Bacterium
Following antibiotic treatment, the disruption of gut microbiota often increases the risk of Clostridioides difficile infection and associated diarrhea. One of the most compelling features of ExoBDNF derived exosome-like vesicles (ExoBDNF-EVs) is their natural targeting capability. In a visual study, EVs labeled in green were shown to successfully locate and enter red-stained Clostridioides difficile bacteria—demonstrating precise delivery at the microbial level.
ExoBDNF™-Suppressing C.
difficile Toxin A Expression
Clostridioides difficile toxin A (TcdA) is a key virulence factor responsible for the pathogen’s detrimental effects. Treatment of C. difficile with ExoBDNF derived exosome-like vesicles (ExoBDNF-EVs) led to a significant reduction in TcdA expression as early as 4 hours, with sustained suppression observed at 9 hours.
For Product Developer
The recommended dose of ExoBDNF™ for a healthy adult is one unit daily according to specific requirements.
Benefits of ExoBDNF™ for Brain
Health:
Your target audience who are
Market-Ready Formula Concepts
The Scientifically Proven, Market-Ready Solution to Set Your Products Apart and Accelerate Your Success
ExoBDNF PRODUCT CONCEPTS
Ingredient:
ExoBDNF
Application:
Supports body balance*
Enhances gut microbiome health*
Promotes healthy digestion*
Helps boost metabolism*
ExoBDNF PRODUCT CONCEPTS
Ingredient:
ExoBDNF
Application:
Helps support mental clarity and organized thinking*
Helps regulate physiological functions*
Helps maintain digestive health*
The communication is intended for business-to-business information and not for the final consumer. These statements have not been evaluated by
the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
